Dietary Supplement to Manage Symptoms of Osteoarthritis: Beneficial Drug Alternative

Dietary supplements are gaining mass popularity on the market. One-third of patients with osteoarthritis have used certain supplements. They are mainly unregulated and marketed without much scientific research to back up their potential effectiveness or safety. While some supplements are proven to be effective and fully safe, others can activate unwanted reactions. Here are some of the most popular dietary supplements to eliminate osteoarthritis symptoms.


This specific dietary supplement is commonly administered by osteoarthritis patients. The organism produces glucosamine naturally, and it can be found in a high concentration within the joints. Theoretically, the substance stimulates cartilage formation, which is inevitable for joint recovery. Synthetic glucosamine features anti-inflammatory properties.

The supplement is available as Glucosamine Sulfate and Glucosamine Hydrochloride. It is widely available in a combination with similar dietary supplements. The component has undergone several medical studies that were aimed at its advantageous influence on hip and knee osteoarthritis treatment. Unfortunately, results of researches were inconsistent.

Conclusions of further research showed a positive influence on osteoarthritis pain reduction. Thus, Glucosamine Sulfate product was found to be one of the most effective osteoarthritis pain reducers. Additionally, another research proved hydrochloride to be also effective in decreasing pain in people with severe instances of the disease.

Compared to NSAIDs or Acetaminophen, Glucosamine Sulfate is more effective in pain reduction and joint function improvement. Besides, the supplement can decrease joint space narrowing within the knee, following several years of the treatment. This dietary supplement is safe for use and not likely to trigger serious side effects.


Chondriotin serves a type of glycosaminoglycan, which is a building block for the structure of joints. The supplement is usually combined with multiple other components, but during the research, Chondroitin features were studied alone.

The medication is not as studied as Glucosamine, while its results are also inconsistent. Early trials of this dietary supplement showed that it possesses useful properties, which can considerably reduce pain and slow down the process of joint space narrowing. The results of recent research have revealed less favorable peculiarities of the medication, concluding that is has no positive influence on osteoarthritis, and have shown that Glucosamine Sulfate is more effective in treatment of the condition that Chondroitin.


S-adenosylmethionine is a naturally produced component that occurs in the liver. The substance is considered to have a favorable influence on cartilage thickness and chondrocytes increase. Besides, it can help reduce chondrocyte damage.

Results of scientific researches in SAM-e for osteoarthritis have been positive and consistent. The supplement was found to be more beneficial than placebo. The effectiveness of osteoarthritis pain relieving power of SAM-e can be compared to NSAIDs.

A recent trial was aimed at comparison of SAM-e with Celebrex. Throughout the first month of the research, Celebrex seemed to be more effective for pain relieving, while after two months of the therapy the medications showed no difference in results. Both treatments were identically advantageous and effective.

SAM-e is generally safe, but its intake can sometimes trigger headache, anxiety, nervousness and insomnia. The supplement can interact with specific supplements, such as Ultram, leading to harmful reactions to the health. Discuss SAM-e use with a qualified doctor.


Methylsulfonylmethane is a usual part of a healthy diet. The component can be found in fruits, meats, vegetables, plants and dairy. Additionally, it is naturally produced in the adrenal gland. According to the results of numerous research, MSM has bright anti-inflammatory properties, which help decrease swelling and pain, though cannot cope with joint stiffness.

MSM is generally safe and well-tolerated by the body. The supplement seems to produce only minor side effects, similar to the ones launched by placebo.

Devil’s Claw

Delivered from an African plant, Devil’s claw features a significant anti-inflammatory effect. The substance inhibits lipoxygenase and COX, decreasing osteoarthritis pain. The treatment is well-tolerated and does not produce severe reactions.


Turmeric is known as a spice added to curry powders. Curcumin, a special pigment, which provides yellow color, serves the active component in turmeric. Curcumin is appreciated for its anti-inflammatory effects, however, there is no scientific proof of its preferable influence on the osteoarthritis treatment.


Inhibiting lipoxygenase and COX, ginger can have anti-inflammatory effects. Additionally, it can influence the tumor necrosis factor, as well as development of inflammatory prostaglandins.